• Pain is one of the most common reasons for people consulting their doctor in Australia. An estimated 1 in 5 adult Australians suffer from chronic pain.
  • Chronic pain is estimated to cost the Australian economy more than $34 billion each year.
  • Every year in Australia, millions of children and adults undergo anaesthesia in relation to surgery. Anaesthesia plays a crucial role in the optimisation of patient outcomes after surgery. 
A high priority of perioperative research is to identify and develop strategies that may prevent or reduce the occurrence of long-term postoperative pain, a common complication of major surgery.
The aim of these trials is to reduce the individual and societal burden of chronic postsurgical pain. 
 
Clinical Professor
Professor Tomás Corcoran

Senior Research Fellow Clinical
A/Professor Nolan McDonnell

Research Nurses
Yvonne Buller
 
Ho, K.M., Rao, S., Honeybul, S., Zellweger, R., Wibrow, B., Lipman, J., Holley, A., Kop, A., Geelhoed, E., Corcoran, T., Misur, P., Edibam, C., Baker, R.I., Chamberlain, J., Forsdyke, C., Rogers, F.B. A Multicentre Trial of Vena Cava Filters in Severely Injured Patients. N Engl J Med. 2019 Jul 25;381(4):328-337 https://doi:10.1056/NEJMoa1806515

Barnes, J., Hunter, J., Harris, S., Shankar-Hari, M., Diouf, E., Jammer, I., Kalkman, C., Klein, A.A., Corcoran, T., Dieleman, S., Grocott, M.P.W., Mythen, M.G., St EPCg. Systematic review and consensus definitions for the standardised endpoints in perioperative medicine (step) initiative: Infection and sepsis. Br J Anaesth 2019; 122:500-508.

Ohashi, Y., Walker, J.C., Zhang, F., Prindiville, F.E., Hanrahan, J.P., Mendelson, R., Corcoran, T
. Preoperative gastric residual volumes in fasted patients measured by bedside ultrasound: a prospective observational study. Anaesth Intensive Care. 2018 Nov;46(6):608-613

Myles, P.S., Bellomo,R., Corcoran, T., Forbes, A., Peyton, P., Story, D., Christophi, C., Leslie, K., McGuinness, S., Parke, R., Serpell, J., Chan, M.T.V., Painter, T., McCluskey, S., Minto, G., Wallace, S.; Australian and New Zealand College of Anaesthetists Clinical Trials Network and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Restrictive versus Liberal Fluid Therapy for Major Abdominal Surgery. N Engl J Med. 2018 Jun 14; 378(24):2263-2274.
https://doi:10.1056/NEJMoa1801601

Barden, A., Phillips, M., Hill, L.M., Fletcher, E.M., Mas, E., Loh, P.S., French, M.A., Ho, K.M., Mori, T.A., Corcoran, T.B. Antiemetic doses of dexamethasone and their e¬ ects on immune cell populations and plasma mediators of infl ammation resolution in healthy volunteers. Prostaglandins Leukot Essent Fatty Acids. 2018 Dec;139:31-39. https://doi:10.1016/j.plefa.2018.11.004